Monoclonal Antibody Process
-
Ab Repertoire
Sequencing
Expression
FusionHybridomas
HAT selection
in Bulk CultureHybridoma LibraryTM
FACS Cloning of
single cellsMonoclonal Ab Cultures
ScreeningExpanded CloneCellsSupntsRNAImmunization
Conventional Mice and Rats
- multiple strains
- auto-immune
- KO’s
Transgenic Mice and Rats
- OmniMouse
- OmniRat
- OmniFlic (fixed light chain)
- UniRat (nanobody) -
Ab Repertoire
Sequencing
Expression
FusionHybridomas
HAT selection
in Bulk CultureHybridoma LibraryTM
FACS Cloning of
single cellsMonoclonal Ab Cultures
ScreeningExpanded CloneCellsSupntsRNAImmunization
Conventional Mice and Rats
- multiple strains
- auto-immune
- KO’s
Transgenic Mice and Rats
- OmniMouse
- OmniRat
- OmniFlic (fixed light chain)
- UniRat (nanobody)