Antibody Gene Sequencing

Obtaining the sequence of your monoclonal antibody is useful for identifying the same, similar, or unique antibodies. It is typically the first step towards antibody engineering and patenting of an antibody. We offer sample preparation and sequencing of mouse, rat and human immunoglobulin V domains, V plus leader, as well as complete Heavy and Light chain sequencing. Sequencing is available for single samples or samples in 96-well plates. Hybridomas are typically sequenced using Sanger sequencing methods. Deep sequencing of B-cells and Hybridoma Libraries™ by next generation sequencing is available for selected applications. The time to obtain gene sequences ranges from 2-4 weeks depending upon the number of samples and type of sequencing.