The specific obstacles inherent in monoclonal antibody discovery may differ from project to project, but the need for a steady, seasoned hand remains constant. Few research organizations can boast the range of experience we have with monoclonal antibody R&D.
By leveraging our expertise with conventional mice, conventional rats, and human antibody-producing transgenic animals, you can:
Accelerate Development
Generate high-affinity antibodies through a rapid, four-week immunization campaign, with clones delivered in as little as 10 weeks.
Design the Right Protocol
Tailor an immunization protocol that matches your specific needs, including the use of multiple adjuvants, immunogens, and other products.
Choose your Pathways
Utilizing multiple discovery methods can help increase the chances of finding the antibody you need. Hybridoma discovery, Single B-cell discovery, and NGS discovery methods can be performed at Antibody Solutions.
Use the Proper Platform(s)
Build on our experience with transgenic, hyperimmune, gene knockout, and human antibody-producing transgenic mice or rats, including OmniAbⓇRodent Platforms, and Alloy.
Screen Hybridoma Libraries Before Cloning
We screen your Hybridoma Library to confirm conversion before you take on more costly cloning steps. And if you need to later in your research and discovery efforts, you can efficiently revisit your library since it’s immortalized in a secure cryopreserved cell bank.
Deploy the Smartest Technologies
Enjoy the benefits of high-throughput flow cytometry to screen and clone single cells without the need for multiple rounds of sub-cloning. While sequencing paired heavy and light chains of single B-cells is the standard methodology for this, we can always suggest appropriate alternative screening cascades. We can explain and utilize a number of in-house assay types, such as ELISA, FACS, and label-free affinity and epitope analysis.
Revealing Research in MAbs
If you're looking for recommendations on how to approach your antibody discovery project, whether fortherapeutic,critical reagent, ordiagnostic purposes, Antibody Solutions can put expertise to work for you. OurCellestivediscovery allows you to employee multiple discovery methods to find your monoclonal antibody.
Put Us to Work for You
Our grasp of the science of monoclonal antibody discovery — when combined with our well-formulated processes and protocols — is why so many organizations have made us a frequent go-to partner. We’d welcome the opportunity to be the same for your research team, so please contact us to discuss your upcoming research needs and objectives.
